Optimal Cellves
Metabolic Health Tool

Glucose Ketone Index Calculator

Enter your fasting blood glucose and blood ketone readings to calculate your GKI and identify your metabolic zone.

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Glucose units
mg/dL — US standard
Blood Glucose
mg/dL
Blood Ketones
mmol/L
High ketosis Glucose Driven Metabolism
GKI Score
Enter values above
Metabolic Zones Reference
GKI Zone Description
> 9
Glucose Driven Metabolism
Elevated glucose with very low or no ketone production. Insulin signaling is high and the body has no ability to use fat for fuel, with no metabolic flexibility.
9
First Sign of Ketosis
Entry level ketosis. Primary fuel source remains glucose, but the body is learning to flip the switch from glucose to fat.
6
Moderate Ketosis
The body is becoming metabolically flexible and fat adapted. Beta-hydroxybutyrate (BHB), the ketone produced by the liver, is being produced in meaningful amounts and cellular recycling (autophagy) begins to ramp up.
3
Deep Ketosis
Fat oxidation is meaningfully improved, cellular recycling increases and insulin levels are low. AMPK (mitochondrial energy) production rises alongside higher BHB output.
1
High Therapeutic Ketosis
High fat burning, cellular recycling and clean up. Low insulin environment.
< 1
Maximum Therapeutic Ketosis*
The highest level of fat oxidation, cellular recycling (autophagy) and inflammation reduction, with strong stem cell activation. *Do not remain in this zone for more than 1–2 days without direction and guidance from your healthcare provider.

GKI = (Blood glucose in mmol/L) ÷ (Blood ketones in mmol/L) · Developed by Dr. Thomas Seyfried · This tool is for educational and monitoring purposes only and is not a medical diagnostic.